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1

Decreased absorption as a possible cause for the lower bioavailability of a sustained-release propranolol

Harumi Takahashi, Hiroyasu Ogata, Ryoichi Warabioka, Kazuko Kashiwada, Mineko Ohira, Kazuhiko Someya

Journal:

Journal of Pharmaceutical Sciences

Year:

1990

Language:

english

File:

PDF, 551 KB

english, 1990

2

New Bioequivalence Studies : Individual Bioequivalence and Population Bioequivalence

NAKAI, Kiyohito, FUJITA, Masahiko, OGATA, Hiroyasu

Journal:

YAKUGAKU ZASSHI

Year:

2000

File:

PDF, 981 KB

2000

3

Enantioselective binding of propranolol, disopyramide, and verapamil to human α1-acid glycoprotein

Kazuhiko Hanada, Toshikuni Ohta, Masahiko Hirai, Miki Arai, Hiroyasu Ogata

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 201 KB

english, 2000

4

Degenerate PCR Primers to Reveal the Diversity of Giant Viruses in Coastal Waters

Li, Yanze, Hingamp, Pascal, Watai, Hiroyasu, Endo, Hisashi, Yoshida, Takashi, Ogata, Hiroyuki

Journal:

Year:

2018

Language:

english

File:

PDF, 3.11 MB

english, 2018

5

PHARMACOKINETICS AND POLYMORPHIC OXIDATION OF DEXTROMETHORPHAN IN A JAPANESE POPULATION

Naomi Nagai, Takashi Kawakubo, Fumiyo Kaneko, Mika Ishii, Raito Shinohara, Yukihisa Saito, Hideo Shimamura, Akihiro Ohnishi, Hiroyasu Ogata

Journal:

Biopharmaceutics & Drug Disposition

Year:

1996

Language:

english

File:

PDF, 676 KB

english, 1996

6

Oxidative Degradation of Sulpyrine by Molecular Oxygen

Sumie Yoshioka, Hiroyasu Ogata, Toshio Shibazaki, Akira Ejima

Journal:

Archiv der Pharmazie

Year:

1979

Language:

english

File:

PDF, 234 KB

english, 1979

7

Relative bioavailability of two disopyramide capsules in humans based on total, unbound, and unbound enantiomer concentrations

Harumi Takahashi, Hiroyasu Ogata, Mikiko Shimizu, Kayoko Hashimoto, Keiso Masuhara, Kazuko Kashiwada, Kazuhiko Someya

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 514 KB

english, 1993

8

Variability in absorption lag time of pyridoxal phosphate under fasting and pre- and post-meal conditions

Harumi Takahashi, Hiroyasu Ogata, Naomi Nagai, Keiko Sugito, Hideo Shimamura

Journal:

Biopharmaceutics & Drug Disposition

Year:

1994

Language:

english

File:

PDF, 607 KB

english, 1994

9

Comparative studies on eight dissolution methods using 21 commercial chloramphenicol tablets and a nondisintegrating benzoic acid tablet

Hiroyasu Ogata, Toshio Shibazaki, Tetsuo Inoue, Akira Ejima

Journal:

Journal of Pharmaceutical Sciences

Year:

1979

Language:

english

File:

PDF, 541 KB

english, 1979

10

Dissolution systems for chloramphenicol tablet bioavailability

Hiroyasu Ogata, Toshio Shibazaki, Tetsuo Inoue, Akira Ejima

Journal:

Journal of Pharmaceutical Sciences

Year:

1979

Language:

english

File:

PDF, 406 KB

english, 1979

11

Bioavailability of griseofulvin from tablets in beagle dogs and correlation with dissolution rate and bioavailability in humans

Nobuo Aoyagi, Hiroyasu Ogata, Nahoko Kaniwa, Masanobu Koibuchi, Toshio Shibazaki, Akira Ejima, Noriyasu Tamaki, Hidetaka Kamimura, Yoshio Katougi, Yukio Omi

Journal:

Journal of Pharmaceutical Sciences

Year:

1982

Language:

english

File:

PDF, 422 KB

english, 1982

12

Bioavailability of griseofulvin from tablets in humans and the correlation with its dissolution rate

Nobuo Aoyagi, Hiroyasu Ogata, Nahoko Kaniwa, Masanobu Koibuchi, Toshio Shibazaki, Akira Ejima

Journal:

Journal of Pharmaceutical Sciences

Year:

1982

Language:

english

File:

PDF, 580 KB

english, 1982

13

Determination of propranolol enantiomers in human plasma and urine and in rat tissues using chiral stationary-phase liquid chromatography

Harumi Takahashi, Satoshi Kanno, Hiroyasu Ogata, Kazuko Kashiwada, Mineko Ohira, Kazuhiko Someya

Journal:

Journal of Pharmaceutical Sciences

Year:

1988

Language:

english

File:

PDF, 344 KB

english, 1988

14

Interaction between erythrocytes from various animals and emulsions stabilized with various lecithins

Fumiyoshi Ishii, Yoshihide Nagasaka, Hiroyasu Ogata

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 397 KB

english, 1989

15

Power analyses of moment analysis parameter in bioequivalence tests

Nahoko Kaniwa, Hiroyasu Ogata, Nobuo Aoyagi, Yasushi Takeda, Mitsuru Uchiyama

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 540 KB

english, 1989

16

Application of the NONMEM method to evaluation of the bioavailability of drug products

Nahoko Kaniwa, Nobuo Aoyagi, Hiroyasu Ogata, Mika Ishii

Journal:

Journal of Pharmaceutical Sciences

Year:

1990

Language:

english

File:

PDF, 621 KB

english, 1990

17

Comparative pharmacokinetics of unbound disopyramide enantiomers following oral administration of racemic disopyramide in humans

Harumi Takahashi, Hiroyasu Ogata, Mikiko Shimizu, Kayoko Hashimoto, Keiso Masuhara, Kazuko Kashiwada, Kazuhiko Someya

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 329 KB

english, 1991

18

Gastric emptying of tablets and granules in humans, dogs, pigs, and stomach-emptying-controlled rabbits

Nobuo Aoyagi, Hiroyasu Ogata, Nahoko Kaniwa, Mitsuru Uchiyama, Yukio Yasuda, Yoshikuni Tanioka

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 534 KB

english, 1992

19

Determination of metoclopramide and its glucuronide and sulphase conjugates in human biological fluids (plasma, urine and bile) by ion-pair high-performance liquid chromatography

Harumi Takahashi, Hiroyasu Ogata, Hirotoshi Echizen, Takashi Ishizaki

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1987

Language:

english

File:

PDF, 621 KB

english, 1987

20

Quantitative determination of unchanged cisplatin in rat kidney and liver by high-performance liquid chromatography

Kazuhiko Hanada, Naomi Nagai, Hiroyasu Ogata

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 400 KB

english, 1995

21

Enantioselective and highly sensitive determination of carvedilol in human plasma and whole blood after administration of the racemate using normal-phase high-performance liquid chromatography

Masako Saito, Junichi Kawana, Tetsuro Ohno, Masahiro Kaneko, Kiyoshi Mihara, Kazuhiko Hanada, Risa Sugita, Natsuki Okada, Sachiko Oosato, Masatoshi Nagayama, Tetsuya Sumiyoshi, Hiroyasu Ogata

Journal:

Journal of Chromatography B

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

22

Determination of rifampicin and its main metabolites in human plasma by high-performance liquid chromatography

Mika Ishii, Hiroyasu Ogata

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1988

Language:

english

File:

PDF, 335 KB

english, 1988

23

Simultaneous determination of disopyramide and its mono-N-dealkylated metabolite enantiomers in human plasma and urine by enantioselective high-performance liquid chromatography

Harumi Takahashi, Akihiro Tamura, Hiroyasu Ogata, Keiso Masuhara

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 762 KB

english, 1990

24

Quantitative determination of disopyramide, verapamil and flecainide enantiomers in rat plasma and tissues by high-performance liquid chromatography

Kazuhiko Hanada, Satoko Akimoto, Keiko Mitsui, Masayuki Hashiguchi, Hiroyasu Ogata

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 110 KB

english, 1998

25

Colour Doppler ultrasonography of a segmental branch of the portal vein is useful for early diagnosis and monitoring of the therapeutic course of veno-occlusive disease after allogenic haematopoietic stem cell transplantation

Kohji Yoshimoto, Kazuaki Yakushiji, Hiroyasu Ijuin, Naofumi Ono, Michitoshi Hashiguchi, Rie Imamura, Hideaki Ogata, Takashi Okamura, Michio Sata, Hiroshi Hashimoto

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 1.38 MB

english, 2001

26

Equivalence in special populations

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2000

Language:

english

File:

PDF, 146 KB

english, 2000

27

Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract

Kuniaki Nakanishi, Sho Ogata, Hirotaka Matsuo, Yoshikatsu Kanai, Hitoshi Endou, Sadayuki Hiroi, Susumu Tominaga, Shinsuke Aida, Hiroyasu Kasamatsu, Toshiaki Kawai

Journal:

Virchows Archiv

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

28

Erythropoietic protoporphyria with fatal liver failure

Akiko Ishibashi, Riko Ogata, Shotaro Sakisaka, Ryukichi Kumashiro, Yuriko Koga, Keiichi Mitsuyama, Ryoko Kuromatsu, Yasuyo Uchimura, Hiroyasu Ijyuin, Kumi Tanaka, Tadashi Iwao, Kunihide Ishii, Michio

Journal:

Journal of Gastroenterology

Year:

1999

Language:

english

File:

PDF, 324 KB

english, 1999

29

Pharmacokinetics and Toxicodynamics of Oxaliplatin in Rats: Application of a Toxicity Factor to Explain Differences in the Nephrotoxicity and Myelosuppression Induced by Oxaliplatin and the Other Platinum Antitumor Derivatives

Kazuhiko Hanada, Makoto Suda, Norihito Kanai, Hiroyasu Ogata

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 222 KB

english, 2010

30

High-performance liquid chromatographic analysis of unchanged cis-diamminedichloroplatinum (cisplatin) in plasma and urine with post-column derivatization

Masafumi Kinoshita, Naomi Yoshimura, Hiroyasu Ogata, Daijiro Tsujino, Toshiaki Takahashi, Satoru Takahashi, Yuji Wada, Kazuhiko Someya, Tetsuro Ohno, Keisou Masuhara, Yoshio Tanaka

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 398 KB

english, 1990

31

Population pharmacokinetics of darbepoetin alfa in haemodialysis and peritoneal dialysis patients after intravenous administration

Hirotaka Takama, Hideji Tanaka, Daisuke Nakashima, Hiroyasu Ogata, Eiji Uchida, Tadao Akizawa, Shozo Koshikawa

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 439 KB

english, 2007

32

Delayed and acute hemolytic transfusion reactions resulting from red cell antibodies and red cell–reactive HLA antibodies

Chikako Takeuchi, Hitoshi Ohto, Saori Miura, Hiroyasu Yasuda, Satoshi Ono, Takashi Ogata

Journal:

Transfusion (Wiley)

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

33

The renal clearance of unchanged cisplatin during furosemide and mannitol diuresis is dependent on glomerular filtration rate in rats

Naomi Nagai, Hiroyasu Ogata

Journal:

Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 132 KB

english, 1996

34

Effect of food on the bioavailability of cyclandelate from commercial capsules

Kaniwa, Nahoko, Ogata, Hiroyasu, Aoyagi, Nobuo, Ejima, Akira, Takahashi, Terutaka, Uezono, Yuko, Imazato, Yuu

Journal:

Clinical Pharmacology & Therapeutics

Year:

1991

Language:

english

File:

PDF, 451 KB

english, 1991

35

Intestinal First-Pass Metabolism of Eperisone in the Rat

Kiyoshi Mihara, Mina Matsumura, Eiji Yoshioka, Kazuhiko Hanada, Hiromitsu Nakasa, Shigeru Ohmori, Mitsukazu Kitada, Hiroyasu Ogata

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

36

Enantioselective Tissue Distribution of the Basic Drugs Disopyramide, Flecainide and Verapamil in Rats: Role of Plasma Protein and Tissue Phosphatidylserine Binding

Kazuhiko Hanada, Satoko Akimoto, Keiko Mitsui, Kiyoshi Mihara, Hiroyasu Ogata

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 560 KB

1998

37

Effects of Disopyramide and Verapamil on Renal Disposition and Nephrotoxicity of Cisplatin in Rats

Kazuhiko Hanada, Kentaro Odaka, Akemi Kudo, Hiroyasu Ogata

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.08 MB

1999

38

A Use of Monte Carlo Integration for Population Pharmacokinetics with Multivariate Population Distribution

Akifumi Yafune, Masato Takebe, Hiroyasu Ogata

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

39

Risk factors for antituberculous chemotherapy-induced hepatotoxicity in Japanese pediatric patients*

Ohkawa, Katsushito, Hashiguchi, Masayuki, Ohno, Keiko, Kiuchi, Chikako, Takahashi, Setsuko, Kondo, Shinya, Echizen, Hirotoshi, Ogata, Hiroyasu

Journal:

Clinical Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

40

Effect of Trimethoprim on the Renal Clearance of Lamivudine in Rats

TAKATOSHI TAKUBO, TOSHIHIRO KATO, JUNJI KINAMI, KAZUHIKO HANADA, HIROYASU OGATA

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 398 KB

english, 2000

41

Effect of Lamivudine on Uptake of Organic Cations by Rat Renal Brush-Border and Basolateral Membrane Vesicles

TAKATOSHI TAKUBO, TOSHIHIRO KATO, JUNJI KINAMI, KAZUHIKO HANADA, HIROYASU OGATA

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

42

Effect of Buthionine Sulphoximine, Glutathione and Methimazole on the Renal Disposition of Cisplatin and on Cisplatin-induced Nephrotoxicity in Rats: Pharmacokinetic-Toxicodynamic Analysis

KAZUHIKO HANADA, YUJI MUKASA, YUKO NOMIZO, HIROYASU OGATA

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

43

Pharmacokinetics and Toxicodynamics of Cisplatin and Its Metabolites in Rats: Relationship between Renal Handling and Nephrotoxicity of Cisplatin

KAZUHIKO HANADA, KIMIE NINOMIYA, HIROYASU OGATA

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

44

Stereoselective pharmacokinetics and pharmacodynamics of disopyramide and its metabolite in rabbits

Masato Horikawa, Misao Yasumuro, Megumi Kanno, Kazuhiko Hanada, Masayuki Hashiguchi, Hiroyasu Ogata

Journal:

Journal of Pharmacy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 167 KB

english, 2001

45

Uptake of lamivudine by rat renal brush border membrane vesicles

Takatoshi Takubo, Toshihiro Kato, Junji Kinami, Kazuhiko Hanada, Hiroyasu Ogata

Journal:

Journal of Pharmacy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

46

Evaluation of sustained-release granules of chlorphenesin carbamate in dogs and humans

Akimoto Masayuki, Furuya Atsushi, Maki Tohru, Yamada Kenji, Suwa Toshio, Ogata Hiroyasu

Journal:

International Journal of Pharmaceutics

Year:

1993

Language:

english

File:

PDF, 902 KB

english, 1993

47

Release and absorption characteristics of chlorphenesin carbamate sustained-release formulations: In vitro-in vivo and in vivo dog-human correlations

Masayuki Akimoto, Atsushi Furuya, Masato Nakamura, Tohru Maki, Kenji Yamada, Toshio Suwa, Hiroyasu Ogata

Journal:

International Journal of Pharmaceutics

Year:

1995

Language:

english

File:

PDF, 608 KB

english, 1995

48

Evaluation of gastrointestinal transit controlled-beagle dog as a suitable animal model for bioavailability testing of sustained-release acetaminophen dosage form

Kenji Yamada, Atsushi Furuya, Masayuki Akimoto, Tohru Maki, Toshio Suwa, Hiroyasu Ogata

Journal:

International Journal of Pharmaceutics

Year:

1995

Language:

english

File:

PDF, 957 KB

english, 1995

49

Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: Effects of carvedilol enantiomers

Kazuhiko Hanada, Kazuhiko Asari, Masako Saito, Jun-ichi Kawana, Mitsuo Mita, Hiroyasu Ogata

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 408 KB

english, 2008

50

Active oxygen species generation and cellular damage by additives of parenteral preparations: selenium and sulfhydryl compounds

Atsushi Terada, Minoru Yoshida, Yoshiyuki Seko, Teruaki Kobayashi, Katsumi Yoshida, Masahiro Nakada, Konosuke Nakada, Hirotoshi Echizen, Hiroyasu Ogata, Tadaaki Rikihisa

Journal:

Year:

1999

Language:

english

File:

PDF, 283 KB

english, 1999

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